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quadriceps, glutes, etc) Progressive loading where possible Protein intake A reasonable evidence-informed target for preserving muscle during weight loss is: 1.21.6 grams of protein per kilogram of body weight per day Many patients on GLP-1 medications unintentionally under-eat protein because appetite is reduced

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scaling the solvent volume adjusts the resulting mg/mL and M concentration accordingly

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These include anorectic effects driven by previously discussed central modulation of satiety and reward pathways and peripheral activation of vagal afferents, delayed gastric emptying, anti-inflammatory properties, potential impact on energy expenditure and the ability to reduce ghrelin levels, which are inherently elevated in PWS (30)

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